ICP-MS: ADVANCED TRAINING ON METHOD VALIDATION AND UNCERTAINITY MEASUREMENT
Since the introduction of Inductively Coupled Plasma – Optical Emission Spectroscopy (ICP OES) in 1974, and Inductively Coupled Plasma Mass Spectrometry (ICP-MS) in 1980, these techniques have revolutionised the simultaneous analysis of major, trace and ultra-trace elements in a wide range of sample matrices. Currently, these instruments are used extensively in diverse areas such as mining, manufacturing, food, and environmental testing. Through a combination of various digestion techniques, samples ranging from high fat foods (such as processed meat, butter) to refractory materials (such as automotive catalysts, ores, soils), can be dissolved, and their elemental content reliably determined. These measurements can be performed with very high accuracy and precision. This training will provide an overview of the basic operating principles of both ICP-OES and ICPMS, focussing on sample preparation, instrument set-up (impact of sample introduction systems), method development, validation as well as quality control aspects. Additionally, an overview will be provided on basic maintenance and trouble shooting. Participants will be introduced to recent developments, such as elemental speciation.Â
• Overview of mass spectrometry and its applications• Principles of inductively coupled plasma and ionization• Key components of an ICP-MS system (plasma torch, ion optics, mass analyzer, detector)• Instrumentation and Setup Detailed discussion of ICP-MS components• Types of mass analysers • Sample introduction systems• Understanding sensitivity, resolution, and dynamic range• Method Development• Instrument setup and calibration for sample analysis • Preparation and analysis samples for various matrices • Running ICP-MS  methods: step-by step guidance • Understanding mass spectra and interpreting results • Quantification methods and the creation of calibration curves• Software tools for data processing and reporting• Data Analysis and Interpretation.
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Event details
ICIPE
Laboratory, ICIPE, Buruburu Business Complex, Mumias South Road, Kasarani, Nairobi, 00100, Kenya
Venue details URLJohn Donald Angira
Chrom Africa Instrumentation Services Limited
Buru buru Business Complex Mumias South Road P. O.Box 4963 00100 Nairobi